Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | DGAT2 | Q96PD7 | 5/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28099271 | 1.00 | SLC6A2 (0.41) | SLC6A2HTR1AHTR2ASLC6A4SLC6A3 | |
| SCHEMBL17077451 | 0.88 | SLC6A2 (0.50) | SLC6A2HTR1AHTR2ASLC6A4SLC6A3 | |
| SCHEMBL17077450 | 0.88 | SLC6A2 (0.50) | SLC6A2HTR1AHTR2ASLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL23582983 | 0.87 | SLC6A2 (0.49) | SLC6A2HTR1AHTR2ASLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL17077567 | 0.87 | SLC6A2 (0.49) | SLC6A2HTR1AHTR2ASLC6A4SLC6A3 | |
| Tert-Butyl Formate SCHEMBL28277465 | 0.85 | HTR2C (0.46) | SLC6A2HTR1ASLC6A4SLC6A3HTR2B | |
| Tert-Butyl Formate SCHEMBL27772363 | 0.83 | SLC6A4 (0.41) | SLC6A4 | |
| Tert-Butyl Formate SCHEMBL27772364 | 0.83 | SLC6A4 (0.41) | SLC6A4 | |
| Cadaverine Tartrate SCHEMBL17077538 | 0.80 | SLC6A2 (0.43) | SLC6A2HTR1AHTR2ASLC6A4SLC6A3 | |
| Cadaverine Tartrate SCHEMBL17077537 | 0.80 | SLC6A2 (0.43) | SLC6A2HTR1AHTR2ASLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106103425-A | Diacylglycerol acyltransferase 2 inhibitors for the treatment of metabolic and related disorders | 辉瑞公司 | 2016-11-09 | — | — | CN | disclosed |