Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TACR1 | P25103 | 9/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860425 | 0.89 | TACR1 (0.50) | KCNK9KDM4EMEN1GMNNLMNA | |
| SCHEMBL9464050 | 0.81 | TACR1 (0.48) | TACR1NPC1MTORRAB9A | |
| SCHEMBL2785002 | 0.79 | TACR1 (0.55) | TACR1NPC1MTORRAB9A | |
| SCHEMBL2858162 | 0.79 | TACR1 (0.55) | TACR1NPC1MTORRAB9A | |
| SCHEMBL2858768 | 0.79 | TACR1 (0.55) | TACR1NPC1MTORRAB9A | |
| SCHEMBL2858767 | 0.79 | TACR1 (0.55) | TACR1NPC1MTORRAB9A | |
| SCHEMBL8800656 | 0.79 | TACR1 (0.55) | TACR1NPC1MTORRAB9A | |
| SCHEMBL11294071 | 0.76 | TACR1 (0.37) | KCNK9KDM4EMEN1GMNNLMNA | |
| SCHEMBL6135412 | 0.76 | TACR1 (0.55) | TACR1NPC1MTORRAB9A | |
| SCHEMBL14364850 | 0.76 | TACR1 (0.55) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103502213-B | Alkaloid ester and carbamate derivatives thereof and medicinal compositions | 奇斯药制品公司 | 2016-09-28 | — | — | CN | claimed |
| CN-103502213-B | Alkaloid ester and carbamate derivatives thereof and medicinal compositions | 奇斯药制品公司 | 2016-09-28 | — | — | CN | disclosed |