Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LSS | P48449 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13517547 | 0.77 | CHRM2 (0.51) | RAB9AGAACHRM5CHRM1CHRM3 | |
| SCHEMBL13516950 | 0.76 | GLA (0.48) | GLANPC1RAB9AGAALSS | |
| SCHEMBL14937275 | 0.75 | MEN1 (0.56) | TSHRALDH1A1MAPT | |
| SCHEMBL14807964 | 0.74 | ALDH1A1 (0.70) | GLANPC1RAB9AGAALSS | |
| SCHEMBL9707102 | 0.73 | LSS (0.67) | GLANPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL3210424 | 0.73 | GLA (0.54) | GLANPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL3210416 | 0.73 | GLA (0.54) | GLANPC1RAB9AGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8988468 | 0.72 | LSS (0.66) | GLANPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL9696817 | 0.71 | ALDH1A1 (0.46) | CHRM5CHRM1CHRM3CHRM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4322280 | 0.68 | ALDH1A1 (0.45) | GAACHRNA7CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103502213-B | Alkaloid ester and carbamate derivatives thereof and medicinal compositions | 奇斯药制品公司 | 2016-09-28 | — | — | CN | disclosed |