Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL30309840 | 0.82 | KMT2A (0.51) | POLBSSTR4KMT2AUSP2FAAH | |
| SCHEMBL6689211 | 0.78 | POLB (0.58) | POLBKMT2AUSP2MAPT | |
| SCHEMBL10091153 | 0.78 | POLB (0.51) | POLBKMT2AUSP2MAPT | |
| SCHEMBL2535206 | 0.76 | POLB (0.63) | POLBKMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL15224114 | 0.76 | POLB (0.68) | POLBKMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL12016121 | 0.76 | SLC6A2 (0.52) | KMT2AUSP2 | |
| SCHEMBL27908646 | 0.74 | POLB (0.70) | POLBKMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL10091197 | 0.74 | POLB (0.48) | POLBKMT2AUSP2MAPT | |
| SCHEMBL28379301 | 0.73 | POLB (0.50) | POLBKMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL20705956 | 0.73 | POLB (0.50) | POLBKMT2AUSP2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103502213-B | Alkaloid ester and carbamate derivatives thereof and medicinal compositions | 奇斯药制品公司 | 2016-09-28 | — | — | CN | claimed |
| CN-103502213-B | Alkaloid ester and carbamate derivatives thereof and medicinal compositions | 奇斯药制品公司 | 2016-09-28 | — | — | CN | disclosed |