Formic Acid

Formic Acid

SCHEMBL28099501

CCc1ccccc1I.O=CO

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.43
GABRA1 P14867 2/20 0.43
GABRB2 P47870 2/20 0.43
IDO1 P14902 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
MGLL Q99685 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 3/20 0.34
ALDH1A1 P00352 2/20 0.34
GAA P10253 1/20 0.34
MAPK8 P45983 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
DAO P14920 1/20 0.33
SIGMAR1 Q99720 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL172963 0.89
Formamide SCHEMBL27667903 0.87 TAAR1 (0.48) TAAR1GABRA1GABRB2IDO1CYP1A2
SCHEMBL12086036 0.86 TAAR1 (0.50) TAAR1GABRA1GABRB2IDO1CYP1A2
Formaldehyde SCHEMBL27915397 0.84 TAAR1 (0.48) TAAR1GABRA1GABRB2IDO1CYP1A2
Methylamine SCHEMBL11265851 0.84 TAAR1 (0.54) TAAR1GABRA1GABRB2IDO1CYP1A2
Formic Acid SCHEMBL27758022 0.84 GABRA1 (0.52) GABRA1GABRB2CYP2D6MGLLPOLB
Acetic Acid SCHEMBL30931543 0.83 CYP1A2 (0.50) TAAR1GABRA1GABRB2IDO1CYP1A2
Propylamine SCHEMBL11274249 0.78 TAAR1 (0.59) TAAR1GABRA1GABRB2IDO1CYP1A2
Formic Acid SCHEMBL27578535 0.78 TDP1 (0.38) TAAR1IDO1CYP1A2CYP2D6CYP2C9
Chlorobenzene SCHEMBL27595529 0.77 TSHR (0.46) TAAR1GABRA1GABRB2IDO1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105980376-A Heterocyclic modulators of lipid synthesis for use against cancer and viral infections 3-V生物科学股份有限公司 2016-09-28 CN disclosed