Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.67 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PHGDH | O43175 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28099696 | 0.83 | F10 (0.73) | F10 | |
| SCHEMBL28834490 | 0.80 | F10 (0.80) | F10KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL28099683 | 0.80 | F10 (1.00) | F10 | |
| SCHEMBL28099689 | 0.80 | F10 (0.82) | F10KMT2A | |
| SCHEMBL28099693 | 0.77 | F10 (1.00) | F10 | |
| SCHEMBL28099533 | 0.77 | F10 (0.81) | F10KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28099691 | 0.77 | F10 (1.00) | F10 | |
| SCHEMBL28099541 | 0.77 | F10 (0.84) | F10KMT2AMAPTPARP1 | |
| SCHEMBL28099685 | 0.77 | F10 (0.79) | F10 | |
| SCHEMBL28099687 | 0.75 | F10 (0.83) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105985276-A | 3,4-dibenzamido benzamide derivative, preparation method and application thereof | 南京中瑞药业有限公司 | 2016-10-05 | — | — | CN | disclosed |