Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | DDX3X | O00571 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3207627 | 0.85 | KMT2A (0.78) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL20984089 | 0.83 | KMT2A (0.65) | KMT2AMEN1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL10433499 | 0.81 | MEN1 (0.63) | KMT2AMEN1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8599639 | 0.80 | KMT2A (0.61) | KMT2AMEN1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL27818795 | 0.78 | SMN1; SMN2 (0.56) | KMT2AMEN1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL16515689 | 0.78 | KMT2A (0.68) | KMT2AMEN1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL31185157 | 0.78 | SMN1; SMN2 (0.68) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL31064998 | 0.77 | KMT2A (0.56) | KMT2AMEN1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL11135290 | 0.77 | MAPT (0.64) | KMT2AMEN1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL10692848 | 0.77 | KMT2A (0.66) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105979950-A | Pyrrolotriazine kinase inhibitors | 百时美施贵宝公司 | 2016-09-28 | — | — | CN | disclosed |