SCHEMBL20984089

SCHEMBL20984089

O=C(NNc1cccc([N+](=O)[O-])c1)C(=O)NNc1cccc([N+](=O)[O-])c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.65
POLB P06746 3/20 0.65
MEN1 O00255 3/20 0.65
MAPT P10636 2/20 0.65
DDX3X O00571 1/20 0.65
HTT P42858 1/20 0.65
CTDSP1 Q9GZU7 1/20 0.65
SMN1; SMN2 Q16637 4/20 0.61
BLM P54132 1/20 0.58
ALDH1A1 P00352 4/20 0.55
TSHR P16473 2/20 0.55
ALOX15 P16050 1/20 0.55
GAA P10253 4/20 0.54
LMNA P02545 2/20 0.53
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
MMP2 P08253 1/20 0.53
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
CES2 O00748 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10433499 0.88 MEN1 (0.63) KMT2APOLBMEN1MAPTDDX3X
SCHEMBL8599639 0.87 KMT2A (0.61) KMT2APOLBMEN1MAPTDDX3X
SCHEMBL11135290 0.83 MAPT (0.64) KMT2APOLBMEN1MAPTDDX3X
SCHEMBL28099549 0.83 KMT2A (0.60) KMT2APOLBMEN1MAPTDDX3X
SCHEMBL31064998 0.83 KMT2A (0.56) KMT2APOLBMEN1MAPTDDX3X
SCHEMBL10518161 0.82 KMT2A (0.55) KMT2APOLBMEN1MAPTDDX3X
SCHEMBL8183254 0.79 ALOX5 (0.62) KMT2APOLBMEN1MAPTDDX3X
SCHEMBL30999886 0.79 ALOX5 (0.62) KMT2APOLBMEN1MAPTDDX3X
SCHEMBL1047211 0.79 MEN1 (1.00) KMT2APOLBMEN1MAPTDDX3X
SCHEMBL9371484 0.79 KMT2A (0.59) KMT2APOLBMEN1MAPTDDX3X

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11040938-B2 Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) 2021-06-22 US claimed
CN-107663161-B Continuous flow synthesis process of phenylhydrazine salt and substituted phenylhydrazine salt 上海惠和化德生物科技有限公司 2020-04-10 CN claimed
US-20190152896-A1 Continuous Flow Process For the Synthesis of Phenylhydrazine Salts and Substituted Phenylhydrazine Salts SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) 2019-05-23 US claimed
US-11040938-B2 Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) 2021-06-22 US disclosed
CN-107663161-B Continuous flow synthesis process of phenylhydrazine salt and substituted phenylhydrazine salt 上海惠和化德生物科技有限公司 2020-04-10 CN disclosed
US-20190152896-A1 Continuous Flow Process For the Synthesis of Phenylhydrazine Salts and Substituted Phenylhydrazine Salts SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) 2019-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11040938-B2 Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts HPD, TYR, PDK2 KMT2A 2660/4885POLB 892/4885MEN1 4774/4885
US-20190152896-A1 Continuous Flow Process For the Synthesis of Phenylhydrazine Salts and Substituted Phenylhydrazine Salts HPD, TYR, PDK2 KMT2A 2660/4885POLB 892/4885MEN1 4774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.