Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL183808 | 0.73 | AKR1B1 (0.36) | AKR1B1 | |
| SCHEMBL27733742 | 0.73 | AKR1B1 (0.36) | AKR1B1 | |
| SCHEMBL27994635 | 0.71 | — | — | |
| SCHEMBL22718863 | 0.70 | AKR1B1 (0.33) | AKR1B1 | |
| SCHEMBL6136757 | 0.70 | AKR1B1 (0.33) | AKR1B1 | |
| SCHEMBL3512421 | 0.70 | AKR1B1 (0.33) | AKR1B1 | |
| SCHEMBL1735273 | 0.70 | AKR1B1 (0.33) | AKR1B1 | |
| SCHEMBL4442654 | 0.70 | AKR1B1 (0.33) | AKR1B1 | |
| SCHEMBL8891164 | 0.70 | AKR1B1 (0.33) | AKR1B1 | |
| SCHEMBL6028034 | 0.70 | AKR1B1 (0.33) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105979951-A | 4' -difluoromethyl substituted nucleoside derivatives as inhibitors of influenza RNA replication | 里博科学有限责任公司 | 2016-09-28 | — | — | CN | claimed |
| CN-105979951-B | 4' -difluoromethyl substituted nucleoside derivatives as inhibitors of influenza RNA replication | 里博科学有限责任公司 | 2020-12-25 | — | — | CN | disclosed |
| CN-105979951-A | 4' -difluoromethyl substituted nucleoside derivatives as inhibitors of influenza RNA replication | 里博科学有限责任公司 | 2016-09-28 | — | — | CN | disclosed |