Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3512421 | 1.00 | AKR1B1 (0.33) | AKR1B1 | |
| SCHEMBL8891164 | 1.00 | AKR1B1 (0.33) | AKR1B1 | |
| SCHEMBL22718863 | 1.00 | AKR1B1 (0.33) | AKR1B1 | |
| SCHEMBL1735273 | 1.00 | AKR1B1 (0.33) | AKR1B1 | |
| SCHEMBL2319494 | 0.87 | AKR1B1 (0.31) | AKR1B1 | |
| SCHEMBL2319604 | 0.87 | AKR1B1 (0.31) | AKR1B1 | |
| SCHEMBL3357559 | 0.87 | AKR1B1 (0.31) | AKR1B1 | |
| SCHEMBL2323878 | 0.87 | AKR1B1 (0.31) | AKR1B1 | |
| SCHEMBL183808 | 0.76 | AKR1B1 (0.36) | AKR1B1 | |
| SCHEMBL4288128 | 0.74 | AKR1B1 (0.36) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097937-B1 | N-acyl derivatives of the LL-E33288 antitumor antibiotics | WYETH CORP (US) | 2005-06-08 | — | — | EP | disclosed |
| EP-0392376-B1 | N-acyl derivatives of the LL-E33288 antitumor antibiotics | AMERICAN CYANAMID CO (US) | 2001-10-31 | — | — | EP | disclosed |
| EP-1097937-A1 | N-acyl derivatives of the LL-E33288 antitumor antibiotics | American Cyanamid Company (US) | 2001-05-09 | — | — | EP | disclosed |
| US-5079233-A | N-acyl derivatives of the LL-E33288 antitumor antibiotics, composition and methods for using the same | AMERICAN CYANAMID COMPANY (US) | 1992-01-07 | — | — | US | disclosed |
| EP-0392376-A2 | N-acyl derivatives of the LL-E33288 antitumor antibiotics | AMERICAN CYANAMID COMPANY (US) | 1990-10-17 | — | — | EP | disclosed |