Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28402036 | 0.95 | ALDH1A1 (0.46) | ALDH1A1TSHRTHRBTDP1ELANE | |
| Bicarbonate SCHEMBL27894778 | 0.95 | ALDH1A1 (0.46) | ALDH1A1TSHRTHRBTDP1ELANE | |
| SCHEMBL35971 | 0.95 | — | — | |
| Methacrylic Acid SCHEMBL5356962 | 0.93 | ALDH1A1 (0.44) | ALDH1A1TSHRTHRBTDP1ELANE | |
| Benzene SCHEMBL5338082 | 0.93 | ALDH1A1 (0.44) | ALDH1A1TSHRTHRBTDP1ELANE | |
| SCHEMBL11854992 | 0.92 | — | — | |
| SCHEMBL28126634 | 0.92 | — | — | |
| SCHEMBL11590228 | 0.92 | — | — | |
| SCHEMBL11256472 | 0.92 | — | — | |
| Water SCHEMBL27430114 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109971402-A | A kind of assembling of wind-power electricity generation magnetic assembly acrylate adhesive and preparation method thereof and its application method | 黑龙江省科学院石油化学研究院 | 2019-07-05 | — | — | CN | claimed |
| CN-109971402-A | A kind of assembling of wind-power electricity generation magnetic assembly acrylate adhesive and preparation method thereof and its application method | 黑龙江省科学院石油化学研究院 | 2019-07-05 | — | — | CN | disclosed |
| CN-109964165-A | Eyeglass and its production method, particularly 3D printing method | 卡尔蔡司光学国际有限公司 | 2019-07-02 | — | — | CN | disclosed |
| CN-105474007-B | Biosensor and method for measuring the same | 国立大学法人东京大学 | 2018-12-07 | — | — | CN | disclosed |
| CN-108779608-A | Paper coating composition and preparation method | 陶氏环球技术有限责任公司 | 2018-11-09 | — | — | CN | disclosed |
| CN-104139180-B | Method of mixing raw material for powder metallurgy, mixer, and binder for injection moulding composition | 柯马杜股份有限公司 | 2017-04-12 | — | — | CN | disclosed |
| CN-106125506-A | Novel polymer and photo-corrosion-resisting agent composition | 罗门哈斯电子材料有限公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-105980155-A | Transparent composite including solar control layer and method of forming the same | 美国圣戈班性能塑料公司 | 2016-09-28 | — | — | CN | disclosed |