Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TMPRSS4 | Q9NRS4 | 4/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365939 | 0.82 | MEN1 (0.48) | TMPRSS4CHRNA7MEN1KMT2AMAPT | |
| SCHEMBL28100494 | 0.78 | P2RX1 (0.41) | MEN1KMT2AMAPTP2RX1HTT | |
| Iodide SCHEMBL5764079 | 0.78 | MEN1 (0.46) | TMPRSS4CHRNA7MEN1KMT2AMAPT | |
| SCHEMBL1369040 | 0.76 | — | — | |
| SCHEMBL323510 | 0.71 | KIF11 (0.48) | MAPT | |
| SCHEMBL225921 | 0.70 | PDE2A (0.53) | GAATMPRSS4CHRNA7MEN1KMT2A | |
| SCHEMBL29430111 | 0.70 | PDE2A (0.53) | GAATMPRSS4CHRNA7MEN1KMT2A | |
| SCHEMBL82230 | 0.70 | NOTUM (0.47) | MCL1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27283036 | 0.70 | TSHR (0.43) | KDRGAAMEN1KMT2AMAPT | |
| Water SCHEMBL29058831 | 0.69 | PDE2A (0.52) | GAATMPRSS4CHRNA7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980392-A | Bromodomain inhibitors | 艾伯维公司 | 2016-09-28 | — | — | CN | disclosed |