Trolnitrate

Trolnitrate

SCHEMBL28100485

O=[N+]([O-])OCCN(CCO[N+](=O)[O-])CCO[N+](=O)[O-].[CH2]C(=O)O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 3/20 0.33
MMP2 P08253 2/20 0.32
MMP9 P14780 2/20 0.32
KCNH2 Q12809 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30
CA9 Q16790 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolnitrate SCHEMBL362506 0.87 ALDH1A1 (0.42) ALDH1A1MMP2MMP9KCNH2CA12
Tenitramine SCHEMBL28086508 0.84 ALDH1A1 (0.40) ALDH1A1MMP2MMP9CA12CA1
Tenitramine SCHEMBL29373173 0.84 ALDH1A1 (0.40) ALDH1A1MMP2MMP9CA12CA1
Trolnitrate SCHEMBL27869649 0.82 ALDH1A1 (0.39) ALDH1A1MMP2MMP9CA12CA1
Trolnitrate SCHEMBL4604021 0.82 ALDH1A1 (0.32) ALDH1A1
Trolnitrate SCHEMBL28114056 0.81 ALDH1A1 (0.39) ALDH1A1KDM4ECA12CA1CA2
Trolnitrate SCHEMBL6390411 0.81 ALDH1A1 (0.34) ALDH1A1HSD17B10MMP2MMP9KMT2A
Trolnitrate SCHEMBL286264 0.81 ALDH1A1 (0.34) ALDH1A1HSD17B10MMP2MMP9KMT2A
Trolnitrate SCHEMBL11423298 0.79 ALDH1A1 (0.33) ALDH1A1
Trolnitrate SCHEMBL9249444 0.79 ALDH1A1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109704654-A A kind of composition for being filled after tunnel wall, consolidation fluid and preparation method 中铁隧道集团三处有限公司 2019-05-03 CN disclosed
CN-106010203-A Aqueous metal based paint composition 关西涂料株式会社 2016-10-12 CN disclosed
CN-106010042-A Aqueous coloring basic paint composition 关西涂料株式会社 2016-10-12 CN disclosed