SCHEMBL28100792

SCHEMBL28100792

NC(=O)/C(=C\C(=O)O)c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 2/20 0.61
PLA2G10 O15496 1/20 0.61
LMNA P02545 2/20 0.51
TBXAS1 P24557 2/20 0.47
SRD5A2 P31213 1/20 0.42
SLC22A2 O15244 1/20 0.42
KMT2A Q03164 1/20 0.40
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40
CALM1 P0DP23 1/20 0.40
PPARG P37231 3/20 0.40
PPARA Q07869 3/20 0.40
MAPK1 P28482 1/20 0.39
CASP3 P42574 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TSHR P16473 1/20 0.39
HNF4A P41235 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28100796 0.90 PLA2G2A (0.61) PLA2G2APLA2G10LMNATBXAS1SRD5A2
SCHEMBL8764232 0.84 CYP2C19 (0.50) LMNAKMT2AMAPK1L3MBTL1TSHR
SCHEMBL27541840 0.84 CYP2C19 (0.50) LMNAKMT2AMAPK1L3MBTL1TSHR
SCHEMBL7121173 0.77 NQO2 (0.56) LMNASRD5A2KMT2APARP10
SCHEMBL7121170 0.77 NQO2 (0.56) LMNASRD5A2KMT2APARP10
SCHEMBL1719129 0.76 PLA2G2A (1.00) PLA2G2APLA2G10LMNASRD5A2SLC22A2
SCHEMBL21063906 0.75 TPMT (0.48) SLC22A2PRSS1PRSS2PRSS3
SCHEMBL9359640 0.74 PLA2G10 (0.52) PLA2G2APLA2G10LMNATBXAS1SRD5A2
SCHEMBL29157755 0.74 PLA2G2A (0.67) PLA2G2APLA2G10LMNASRD5A2SLC22A2
Diphenylmethane SCHEMBL18604552 0.73 PLA2G10 (0.71) PLA2G2APLA2G10LMNASLC22A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106104333-A Retardation film, and polarizing plate and display device using same 柯尼卡美能达株式会社 2016-11-09 CN disclosed