SCHEMBL28100894

SCHEMBL28100894

N#Cc1ccc(P(=O)(Oc2ccccc2)Oc2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.66
L3MBTL1 Q9Y468 1/20 0.66
CA1 P00915 7/20 0.49
CA2 P00918 7/20 0.49
CA9 Q16790 7/20 0.49
CA12 O43570 6/20 0.49
CA4 P22748 6/20 0.49
CA5A P35218 6/20 0.49
CA7 P43166 6/20 0.49
CA5B Q9Y2D0 6/20 0.49
TSHR P16473 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C19 P33261 1/20 0.45
MAOB P27338 2/20 0.43
SRC P12931 1/20 0.42
MAOA P21397 1/20 0.40
NR3C1 P04150 1/20 0.38
PGR P06401 1/20 0.38
KDM4E B2RXH2 1/20 0.38
F2 P00734 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21815469 0.93 TDP1 (0.66) TDP1L3MBTL1CA1CA2CA9
SCHEMBL28101013 0.82 L3MBTL1 (0.66) TDP1L3MBTL1CA1CA2CA9
SCHEMBL28460825 0.81 MAOB (0.50) TDP1L3MBTL1CA1CA2CA9
SCHEMBL561190 0.80 L3MBTL1 (1.00) TDP1L3MBTL1CA1CA2CA9
Carbon Monoxide SCHEMBL6562620 0.79 L3MBTL1 (0.87) TDP1L3MBTL1CA1CA2CA9
SCHEMBL14566904 0.79 L3MBTL1 (0.79) TDP1L3MBTL1CA1CA2CA9
SCHEMBL28383839 0.79 MAOB (0.47) TDP1L3MBTL1CA1CA2CA9
SCHEMBL29157902 0.77 L3MBTL1 (0.76) TDP1L3MBTL1CA1CA2CA9
SCHEMBL483046 0.77 L3MBTL1 (0.76) TDP1L3MBTL1CA1CA2CA9
SCHEMBL28136591 0.77 L3MBTL1 (0.83) TDP1L3MBTL1CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105968136-B A kind of preparation method of fragrance phosphonate compound 北京大学 2018-12-07 CN disclosed
CN-105968136-A Preparation method of aromatic phosphonate compound 北京大学 2016-09-28 CN disclosed