Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | PPARD | Q03181 | 6/20 | 0.40 |
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octane SCHEMBL28360215 | 1.00 | TSHR (0.52) | TSHRHPGDZDHHC20ZDHHC2THRB | |
| Tetradecane SCHEMBL28204017 | 1.00 | TSHR (0.52) | TSHRHPGDZDHHC20ZDHHC2THRB | |
| SCHEMBL28326776 | 1.00 | TSHR (0.52) | TSHRHPGDZDHHC20ZDHHC2THRB | |
| Hexadecane SCHEMBL28137653 | 0.98 | TSHR (0.50) | TSHRHPGDZDHHC20ZDHHC2THRB | |
| Hexane SCHEMBL28069832 | 0.98 | TSHR (0.53) | TSHRHPGDZDHHC20ZDHHC2THRB | |
| Decanoic Acid SCHEMBL28094400 | 0.91 | GPR84 (0.57) | TSHRALDH1A1PPARGPPARDPPARA | |
| SCHEMBL28236951 | 0.91 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4FAAH | |
| SCHEMBL28847578 | 0.91 | TSHR (0.49) | TSHRHPGDZDHHC20ZDHHC2THRB | |
| Palmitic Acid SCHEMBL28107075 | 0.91 | GPR84 (0.57) | TSHRALDH1A1PPARGPPARDPPARA | |
| SCHEMBL27572510 | 0.91 | TSHR (0.49) | TSHRHPGDZDHHC20ZDHHC2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103826661-B | Novel binding agent-drug conjugates (ADCs) and uses thereof | 西雅图基因公司 | 2019-03-05 | — | — | CN | disclosed |
| CN-106117312-A | New bonding agent drug conjugate (ADC) and application thereof | 西雅图基因公司 | 2016-11-16 | — | — | CN | disclosed |