Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Glutathione. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.90 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.90 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.63 |
| ▸ | NOD1 | Q9Y239 | 8/20 | 0.48 |
| ▸ | FNTA | P49354 | 2/20 | 0.41 |
| ▸ | FNTB | P49356 | 2/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutathione SCHEMBL17629816 | 1.00 | PTGS1 (0.90) | PTGS1GSTK1GLO1NOD1FNTA | |
| Glutathione SCHEMBL28101166 | 1.00 | PTGS1 (0.90) | PTGS1GSTK1GLO1NOD1FNTA | |
| Glutathione SCHEMBL4958127 | 0.95 | PTGS1 (0.90) | PTGS1GSTK1GLO1NOD1FNTA | |
| Glutathione SCHEMBL3790504 | 0.95 | PTGS1 (0.95) | PTGS1GSTK1GLO1NOD1FNTA | |
| Glutathione SCHEMBL3790499 | 0.95 | PTGS1 (0.95) | PTGS1GSTK1GLO1NOD1FNTA | |
| Glutathione SCHEMBL5167025 | 0.95 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FNTA | |
| Glutathione SCHEMBL15701576 | 0.95 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FNTA | |
| Glutathione SCHEMBL272141 | 0.95 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FNTA | |
| Glutathione SCHEMBL13105609 | 0.95 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FNTA | |
| Glutathione SCHEMBL5167030 | 0.95 | PTGS1 (1.00) | PTGS1GSTK1GLO1NOD1FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106220708-B | Method for extracting and separating glutathione from GSCu precipitate | 上海青平药业有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-106008664-B | Efficient separation and purification method of glutathione | 上海青平药业有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-110917062-A | Nano emulsion for promoting hair growth and preparation method thereof | 广州韩金靓化妆品有限公司 | 2020-03-27 | — | — | CN | claimed |
| CN-106220708-A | A kind of method extracting separating glutathione from GSCu precipitates | 上海青平药业有限公司 | 2016-12-14 | — | — | CN | claimed |
| CN-106008664-A | Efficient separation and purification method of glutathione | 上海青平药业有限公司 | 2016-10-12 | — | — | CN | claimed |
| CN-106220708-B | Method for extracting and separating glutathione from GSCu precipitate | 上海青平药业有限公司 | 2020-04-10 | — | — | CN | disclosed |
| CN-106008664-B | Efficient separation and purification method of glutathione | 上海青平药业有限公司 | 2020-04-10 | — | — | CN | disclosed |
| CN-110917062-A | Nano emulsion for promoting hair growth and preparation method thereof | 广州韩金靓化妆品有限公司 | 2020-03-27 | — | — | CN | disclosed |
| CN-106220708-A | A kind of method extracting separating glutathione from GSCu precipitates | 上海青平药业有限公司 | 2016-12-14 | — | — | CN | disclosed |
| CN-106008664-A | Efficient separation and purification method of glutathione | 上海青平药业有限公司 | 2016-10-12 | — | — | CN | disclosed |