Glutathione

Glutathione

SCHEMBL5167030

NC(CCC(=O)NC(CS)C(=O)NCC(=O)O)C(=O)O.NC(CCC(=O)NC(CS)C(=O)NCC(=O)O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 1.00
GSTK1 Q9Y2Q3 1/20 1.00
GLO1 Q04760 2/20 0.65
NOD1 Q9Y239 7/20 0.46
FOLH1 Q04609 2/20 0.43
GRM8 O00222 1/20 0.43
GRM6 O15303 1/20 0.43
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GSR P00390 1/20 0.43
CYP1A2 P05177 1/20 0.43
GRIK1 P39086 1/20 0.43
GRM5 P41594 1/20 0.43
GRIA1 P42261 1/20 0.43
GRIA2 P42262 1/20 0.43
GRIA3 P42263 1/20 0.43
SLC1A3 P43003 1/20 0.43
SLC1A2 P43004 1/20 0.43
SLC1A1 P43005 1/20 0.43
GRIA4 P48058 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutathione SCHEMBL28505216 1.00 PTGS1 (1.00) PTGS1GSTK1GLO1NOD1FOLH1
Glutathione SCHEMBL14364095 1.00 PTGS1 (1.00) PTGS1GSTK1GLO1NOD1FOLH1
Glutathione SCHEMBL272141 1.00 PTGS1 (1.00) PTGS1GSTK1GLO1NOD1FOLH1
Glutathione SCHEMBL5167025 1.00 PTGS1 (1.00) PTGS1GSTK1GLO1NOD1FOLH1
Glutathione SCHEMBL13105609 1.00 PTGS1 (1.00) PTGS1GSTK1GLO1NOD1FOLH1
Glutathione SCHEMBL7469803 1.00 PTGS1 (1.00) PTGS1GSTK1GLO1NOD1FOLH1
Glutathione SCHEMBL9167 1.00 PTGS1 (1.00) PTGS1GSTK1GLO1NOD1FOLH1
Glutathione SCHEMBL15701576 1.00 PTGS1 (1.00) PTGS1GSTK1GLO1NOD1FOLH1
Glutathione SCHEMBL1105665 1.00 PTGS1 (1.00) PTGS1GSTK1GLO1NOD1FOLH1
Glutathione SCHEMBL30733475 1.00 PTGS1 (1.00) PTGS1GSTK1GLO1NOD1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014143383-A1 TRANSPOSOME TETHERED TO A GENE DELIVERY VEHICLE AGILENT TECHNOLOGIES, INC. (US) 2014-09-18 WO claimed
EP-0869809-B1 OXIDIZED GLUTATHIONE AS CYTOKINE AND HEMOPOIETIC FACTOR ENDOGENOUS PRODUCTION ENHANCER NOVELOS THERAPEUTICS INC (US) 2002-03-27 EP claimed
CN-122005845-A Targeting nanoparticle for breast cancer treatment and preparation and application thereof 中国人民解放军空军军医大学 2026-05-12 CN disclosed
US-20260078173-A1 SINGLE-CHAIN ZAGOTENEMAB ANTIBODY-TRANSFERRIN FUSION PROTEIN FOR ENHANCED EFFICACY AND INDICATIONS RNA THERAPEUTICS INC (US) 2026-03-19 US disclosed
US-20260078174-A1 SINGLE-CHAIN MEDI1341 ANTIBODY-TRANSFERRIN FUSION PROTEIN FOR ENHANCED EFFICACY AND INDICATIONS RNA THERAPEUTICS INC (US) 2026-03-19 US disclosed
US-20260071004-A1 SINGLE-CHAIN TRASTUZUMAB ANTIBODY-TRANSFERRIN FUSION PROTEIN FOR ENHANCED EFFICACY AND INDICATIONS RNA THERAPEUTICS INC (US) 2026-03-12 US disclosed
US-20260070968-A1 SINGLE-CHAIN USTEKINUMAB ANTIBODY-TRANSFERRIN FUSION PROTEIN FOR ENHANCED EFFICACY AND INDICATIONS RNA THERAPEUTICS INC (US) 2026-03-12 US disclosed
EP-4469560-B1 AN IMPROVED CELL CULTURE MEDIUM FOR CRUSTACEAN CELLS UNIV GENT (BE) 2026-03-11 EP disclosed
US-20260062489-A1 SINGLE-CHAIN TEPROTUMUMAB ANTIBODY-TRANSFERRIN FUSION PROTEIN FOR ENHANCED EFFICACY AND INDICATIONS RNA THERAPEUTICS INC (US) 2026-03-05 US disclosed
US-20260062473-A1 SINGLE-CHAIN TILDRAKIZUMAB ANTIBODY-TRANSFERRIN FUSION PROTEIN FOR ENHANCED EFFICACY AND INDICATIONS RNA THERAPEUTICS INC (US) 2026-03-05 US disclosed
US-20260062467-A1 SINGLE-CHAIN SOLANEZUMAB ANTIBODY-TRANSFERRIN FUSION PROTEIN FOR ENHANCED EFFICACY AND INDICATIONS RNA THERAPEUTICS INC (US) 2026-03-05 US disclosed
US-5220035-A Test compositions which generate different hues at different analyte concentrations MILES INC. (US) 1993-06-15 US disclosed
US-5190863-A Composition for determining the presence or concentration of D-β-hydroxybutyrate MILES INC. (US) 1993-03-02 US disclosed
EP-0438386-A4 NOVEL IMPROVERS FOR FLOUR AND YEAST RAISED BAKED GOODS 1991-09-11 EP disclosed
US-5041658-A Indicator generates a variety of hues depending on the analyte concentration MILES INC. (US) 1991-08-20 US disclosed
EP-0438386-A1 NOVEL IMPROVERS FOR FLOUR AND YEAST RAISED BAKED GOODS GEORGE WESTON FOODS LIMITED (AU) 1991-07-31 EP disclosed
US-4988517-A ANTITUMOR AGENTS, BENZYLSELENOCYANATE, INCREASING GLUTATHIONE PEROXIDASE AMERICAN HEALTH FOUNDATION (US) 1991-01-29 US disclosed
US-4975367-A Catalytic test composition intended to produce a range of colors MILES INC. (US) 1990-12-04 US disclosed
US-4898813-A Catalytic test composition intended to produce a range of colors MILES INC. 1990-02-06 US disclosed
WO-1988003365-A1 NOVEL IMPROVERS FOR FLOUR AND YEAST RAISED BAKED GOODS GEORGE WESTON FOODS LIMITED (AU) 1988-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071004-A1 SINGLE-CHAIN TRASTUZUMAB ANTIBODY-TRANSFERRIN FUSION PROTEIN FOR ENHANCED EFFICACY AND INDICATIONS CD4, TFRC, VAMP8 PTGS1 4692/4885GSTK1 2591/4885GLO1 3901/4885
US-20260070968-A1 SINGLE-CHAIN USTEKINUMAB ANTIBODY-TRANSFERRIN FUSION PROTEIN FOR ENHANCED EFFICACY AND INDICATIONS CD4, CD47, TFRC PTGS1 3952/4885GSTK1 2959/4885GLO1 4119/4885
US-20260062489-A1 SINGLE-CHAIN TEPROTUMUMAB ANTIBODY-TRANSFERRIN FUSION PROTEIN FOR ENHANCED EFFICACY AND INDICATIONS CD4, TFRC, VAMP8 PTGS1 4627/4885GSTK1 2503/4885GLO1 3250/4885
US-20260062473-A1 SINGLE-CHAIN TILDRAKIZUMAB ANTIBODY-TRANSFERRIN FUSION PROTEIN FOR ENHANCED EFFICACY AND INDICATIONS CD4, TFRC, VAMP8 PTGS1 4737/4885GSTK1 2330/4885GLO1 3896/4885
US-20260078174-A1 SINGLE-CHAIN MEDI1341 ANTIBODY-TRANSFERRIN FUSION PROTEIN FOR ENHANCED EFFICACY AND INDICATIONS TFRC, CD4, FCGR3B PTGS1 4647/4885GSTK1 1773/4885GLO1 3014/4885
US-20260062467-A1 SINGLE-CHAIN SOLANEZUMAB ANTIBODY-TRANSFERRIN FUSION PROTEIN FOR ENHANCED EFFICACY AND INDICATIONS CD4, TFRC, VAMP8 PTGS1 4654/4885GSTK1 2972/4885GLO1 3059/4885
US-20260078173-A1 SINGLE-CHAIN ZAGOTENEMAB ANTIBODY-TRANSFERRIN FUSION PROTEIN FOR ENHANCED EFFICACY AND INDICATIONS CD4, TFRC, FCGR3B PTGS1 4417/4885GSTK1 2420/4885GLO1 4018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.