SCHEMBL28101236

SCHEMBL28101236

OC[C@H]1CN(c2ccc(Br)c(F)c2)CO1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CALML3 P27482 6/20 0.39
KDM1A O60341 2/20 0.32
KCNH2 Q12809 2/20 0.32
KDM1B Q8NB78 1/20 0.32
MAOA P21397 3/20 0.31
MAOB P27338 3/20 0.31
GHSR Q92847 1/20 0.31
CYP2C19 P33261 2/20 0.31
CYP2C9 P11712 1/20 0.31
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28218931 0.86 KCNH2 (0.35) CALML3KDM1AKCNH2KDM1BGHSR
SCHEMBL28218930 0.80 ALDH1A1 (0.34) CYP2C19CYP2C9CYP3A4
SCHEMBL441045 0.76 CALML3 (0.65) CALML3MAOAMAOBCYP2C19CYP2C9
SCHEMBL29406421 0.76 CALML3 (0.65) CALML3MAOAMAOBCYP2C19CYP2C9
SCHEMBL30768255 0.76 CALML3 (0.65) CALML3MAOAMAOBCYP2C19CYP2C9
SCHEMBL29021122 0.76 CALML3 (0.65) CALML3MAOAMAOBCYP2C19CYP2C9
SCHEMBL30468631 0.76 CALML3 (0.65) CALML3MAOAMAOBCYP2C19CYP2C9
SCHEMBL412800 0.76 CALML3 (0.65) CALML3MAOAMAOBCYP2C19CYP2C9
SCHEMBL24296107 0.75 CALML3 (0.47) CALML3MAOAMAOBCYP2C19CYP2C9
SCHEMBL27820777 0.73 CALML3 (0.35) CALML3CYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114315898-B Preparation method of tedizolid phosphate and intermediate thereof, and injection 山西振东泰盛制药有限公司 2024-01-12 CN claimed
CN-114933596-B Preparation method of tedizolid 河北广祥制药有限公司 2023-09-05 CN claimed
CN-113214239-B Tedizolid refining process and preparation method of tedizole phosphate 海南通用康力制药有限公司 2023-04-07 CN claimed
CN-114933596-A Preparation method of tedizolid 河北广祥制药有限公司 2022-08-23 CN claimed
CN-116297921-B Texazolamide phosphate method for detecting isomer of intermediate 成都美域高制药有限公司 2025-07-25 CN disclosed
CN-117645605-A Preparation method of high-purity tedizolid phosphate intermediate 安徽森吉制药有限公司 2024-03-05 CN disclosed
CN-114933596-B Preparation method of tedizolid 河北广祥制药有限公司 2023-09-05 CN disclosed
CN-114933596-B Preparation method of tedizolid 河北广祥制药有限公司 2023-09-05 CN disclosed
CN-116297921-A Isomer detection method of tedizolid phosphate intermediate 成都美域高制药有限公司 2023-06-23 CN disclosed
CN-113214239-B Tedizolid refining process and preparation method of tedizole phosphate 海南通用康力制药有限公司 2023-04-07 CN disclosed
CN-114933596-A Preparation method of tedizolid 河北广祥制药有限公司 2022-08-23 CN disclosed
CN-114933596-A Preparation method of tedizolid 河北广祥制药有限公司 2022-08-23 CN disclosed
CN-111518135-B Preparation method of high-purity tedizolid phosphate 山东中医药大学 2022-05-06 CN disclosed
CN-108135887-A Oxazolidinone compounds and its application method as antiseptic 默沙东公司 2018-06-08 CN disclosed
CN-105985331-A Process for preparing tedizolid 上海医药工业研究院 2016-10-05 CN disclosed