Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14648918 | 1.00 | TSHR (0.37) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL4959416 | 0.77 | TSHR (0.31) | TSHRMAPK1HSD17B10TDP1 | |
| SCHEMBL17695754 | 0.66 | ABAT (0.31) | TSHRMAPK1HSD17B10TDP1 | |
| SCHEMBL17686901 | 0.66 | ABAT (0.31) | TSHRMAPK1HSD17B10TDP1 | |
| SCHEMBL156544 | 0.66 | POLB (0.36) | TDP1 | |
| SCHEMBL11579330 | 0.66 | POLB (0.36) | TDP1 | |
| SCHEMBL14648913 | 0.65 | ABAT (0.33) | — | |
| Ammonia Solution, Strong SCHEMBL29216789 | 0.63 | POLB (0.35) | TDP1 | |
| Ammonia Solution, Strong SCHEMBL29216790 | 0.63 | POLB (0.35) | TDP1 | |
| Water SCHEMBL27554144 | 0.63 | POLB (0.35) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106010999-A | Gene engineering strain, culturing method and application of gene engineering strain | 上海交通大学 | 2016-10-12 | — | — | CN | disclosed |