Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14648918 | 0.77 | TSHR (0.37) | TSHRMAPK1HSD17B10TDP1 | |
| SCHEMBL28101799 | 0.77 | TSHR (0.37) | TSHRMAPK1HSD17B10TDP1 | |
| SCHEMBL172436 | 0.69 | — | — | |
| SCHEMBL156544 | 0.67 | POLB (0.36) | TDP1 | |
| SCHEMBL11579330 | 0.67 | POLB (0.36) | TDP1 | |
| SCHEMBL29519432 | 0.67 | — | — | |
| Ammonia Solution, Strong SCHEMBL29216790 | 0.65 | POLB (0.35) | TDP1 | |
| SCHEMBL9695864 | 0.65 | POLB (0.35) | TDP1 | |
| Water SCHEMBL27554144 | 0.65 | POLB (0.35) | TDP1 | |
| Ammonia Solution, Strong SCHEMBL29216789 | 0.65 | POLB (0.35) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10035826-B2 | Proteins and nucleic acids from meningitis/sepsis-associated Escherichia coli | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2018-07-31 | — | — | US | disclosed |
| US-20160244489-A1 | PROTEINS AND NUCLEIC ACIDS FROM MENINGITIS/SEPSIS-ASSOCIATED ESCHERICHIA COLI | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2016-08-25 | — | — | US | disclosed |
| US-9334313-B2 | Proteins and nucleic acids from meningitis/sepsis-associated Escherichia coli | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2016-05-10 | — | — | US | disclosed |
| US-20140356389-A1 | PROTEINS AND NUCLEIC ACIDS FROM MENINGITIS/SEPSIS-ASSOCIATED ESCHERICHIA COLI | J. CRAIG VENTER INSTITUTE, INC. (US) | 2014-12-04 | — | — | US | disclosed |
| US-8758764-B2 | Proteins and nucleic acids from meningitis/sepsis-associated Escherichia coli | NOVARTIS VACCINES AND DIAGNOSTICS SRL (IT) | 2014-06-24 | — | — | US | disclosed |
| US-20080193470-A1 | For immunizing against MNEC infections | GLAXOSMITHKLINE VACCINES S.R.L. (BE) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140356389-A1 | PROTEINS AND NUCLEIC ACIDS FROM MENINGITIS/SEPSIS-ASSOCIATED ESCHERICHIA COLI | SNRPE, NSUN3, DNASE1 | TSHR 4646/4885MAPK1 2686/4885HSD17B10 4543/4885 |
| US-10035826-B2 | Proteins and nucleic acids from meningitis/sepsis-associated Escherichia coli | SNRPE, NSUN3, DNASE1 | TSHR 4638/4885MAPK1 2693/4885HSD17B10 4548/4885 |
| US-20160244489-A1 | PROTEINS AND NUCLEIC ACIDS FROM MENINGITIS/SEPSIS-ASSOCIATED ESCHERICHIA COLI | SNRPE, NSUN3, DNASE1 | TSHR 4646/4885MAPK1 2686/4885HSD17B10 4543/4885 |
| US-20080193470-A1 | For immunizing against MNEC infections | MLEC, GMFG, MYD88 | TSHR 4752/4885MAPK1 2922/4885HSD17B10 4700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.