Phenol

Phenol

SCHEMBL28101899

Cc1cccc(C2CCCCC2)c1.Oc1ccccc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 2/20 0.54
KMO O15229 1/20 0.51
HDAC4 P56524 1/20 0.49
HDAC2 Q92769 1/20 0.49
HDAC8 Q9BY41 1/20 0.49
DRD2 P14416 2/20 0.47
DRD4 P21917 2/20 0.47
DRD1 P21728 1/20 0.47
DRD5 P21918 1/20 0.47
DRD3 P35462 1/20 0.47
ACHE P22303 1/20 0.46
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
XBP1 P17861 1/20 0.44
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL28089938 0.90 KMO (0.61) KMOHDAC4HDAC2HDAC8DRD2
SCHEMBL3062414 0.88 HTR2C (0.67) HTR2CKMOHDAC4HDAC2HDAC8
SCHEMBL27434393 0.88 HTR2C (0.67) HTR2CKMOHDAC4HDAC2HDAC8
Phenol SCHEMBL28176207 0.86 HDAC4 (0.42) HTR2CKMOHDAC4HDAC2HDAC8
SCHEMBL3069922 0.86 HTR2C (0.69) HTR2CKMOHDAC4HDAC2HDAC8
Phenol SCHEMBL11482901 0.82 SLC18A3 (0.53) KMOHDAC4HDAC2HDAC8SMN1; SMN2
Phenol SCHEMBL28098180 0.82 SLC18A3 (0.53) KMOHDAC4HDAC2HDAC8SMN1; SMN2
SCHEMBL2538410 0.82 HTR2C (0.69) HTR2CKMOHDAC4HDAC2HDAC8
SCHEMBL1982025 0.81 HDAC4 (0.59) KMOHDAC4HDAC2HDAC8DRD2
SCHEMBL3356779 0.81 HDAC4 (0.59) KMOHDAC4HDAC2HDAC8DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103998617-B The manufacture method of lignin analyte 花王株式会社 2016-09-28 CN disclosed