Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1348958 | 0.79 | ALDH1A1 (0.54) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL2317723 | 0.79 | ALDH1A1 (0.51) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL4023657 | 0.79 | ALDH1A1 (0.51) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL27098919 | 0.79 | ALDH1A1 (0.51) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11822090 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL4277463 | 0.77 | ALDH1A1 (0.61) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL8541158 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL13519605 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL5660666 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL15715957 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TDP1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103635458-B | Trpv1 antagonists | 艾伯维公司 | 2016-10-19 | — | — | CN | disclosed |