Nitrosobenzene

Nitrosobenzene

SCHEMBL28102490

CO.O=Nc1ccccc1

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
HSD17B10 Q99714 3/20 0.52
TSHR P16473 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
CYP3A4 P08684 1/20 0.52
HTT P42858 1/20 0.52
NOS3 P29474 2/20 0.46
NOS1 P29475 2/20 0.46
MAPK1 P28482 2/20 0.44
TP53 P04637 1/20 0.44
HIF1A Q16665 1/20 0.44
KMT2A Q03164 4/20 0.42
CASP3 P42574 2/20 0.42
SENP7 Q9BQF6 2/20 0.42
SENP6 Q9GZR1 2/20 0.42
PKM P14618 1/20 0.42
HTR3E A5X5Y0 1/20 0.42
SLC22A2 O15244 1/20 0.42
SLC22A1 O15245 1/20 0.42
SLC22A3 O75751 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrosobenzene SCHEMBL103117 0.91
Nitrosobenzene SCHEMBL28014686 0.91 ALDH1A1 (0.59) ALDH1A1HSD17B10TSHRTDP1CYP3A4
Nitrosobenzene SCHEMBL3176061 0.91
Nitrosobenzene SCHEMBL27497449 0.89 ALDH1A1 (0.48) ALDH1A1HSD17B10TSHRTDP1CYP3A4
Nitrosobenzene SCHEMBL27784202 0.89 ALDH1A1 (0.48) ALDH1A1HSD17B10TSHRTDP1CYP3A4
Nitrosobenzene SCHEMBL28787012 0.88 ALDH1A1 (0.52) ALDH1A1HSD17B10TSHRTDP1CYP3A4
Nitrosobenzene SCHEMBL30901881 0.88
Nitrosobenzene SCHEMBL26970890 0.88
Nitrosobenzene SCHEMBL28230134 0.88
Nitrosobenzene SCHEMBL27642000 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109694472-A Functionalised polyethers initiator and its synthesis and the application in polyethers synthesis 万华化学集团股份有限公司 2019-04-30 CN claimed
CN-106008458-A Azobenzene compound and preparation method thereof 上海交通大学 2016-10-12 CN claimed
CN-109694472-A Functionalised polyethers initiator and its synthesis and the application in polyethers synthesis 万华化学集团股份有限公司 2019-04-30 CN disclosed
CN-109694472-A Functionalised polyethers initiator and its synthesis and the application in polyethers synthesis 万华化学集团股份有限公司 2019-04-30 CN disclosed
CN-106008458-A Azobenzene compound and preparation method thereof 上海交通大学 2016-10-12 CN disclosed