SCHEMBL28102804

SCHEMBL28102804

CC(Cc1ccccc1)[PH](=O)O.[NaH]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
TRPA1 O75762 2/20 0.47
TAAR1 Q96RJ0 5/20 0.47
SLC6A2 P23975 2/20 0.47
SIGMAR1 Q99720 2/20 0.47
MAOA P21397 1/20 0.47
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47
CYP2A6 P11509 1/20 0.47
ADORA2A P29274 1/20 0.47
ADORA1 P30542 1/20 0.47
CYP1A2 P05177 1/20 0.45
CPA1 P15085 2/20 0.44
CPB1 P15086 1/20 0.44
CPA3 P15088 1/20 0.44
CPB2 Q96IY4 1/20 0.44
SLC18A2 Q05940 1/20 0.44
CYP2D6 P10635 1/20 0.44
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8467572 0.98 NPC1 (0.48) NPC1RAB9ATRPA1TAAR1SLC6A2
Isobutylbenzene SCHEMBL27855821 0.79 PTGS1 (0.50) NPC1RAB9ATRPA1TAAR1SLC6A2
SCHEMBL30598261 0.77 CYP1A2 (0.50) NPC1RAB9ATRPA1CYP1A2CPA1
SCHEMBL8728958 0.75 CYP1A2 (0.48) TRPA1TAAR1CYP1A2CPA1CPB1
SCHEMBL10914575 0.73 CYP1A2 (0.47) NPC1RAB9ACYP1A2CPA1CPB1
SCHEMBL2517901 0.73 CYP1A2 (0.47) CYP1A2CPA1CPB1CPA3CPB2
SCHEMBL16836842 0.73 ALPI (0.53) TAAR1SLC6A2SIGMAR1MAOASLC6A4
SCHEMBL3862224 0.73 ALPI (0.53) TAAR1SLC6A2SIGMAR1MAOASLC6A4
Bromide SCHEMBL6929745 0.72 ALPI (0.52) TAAR1SLC6A2SIGMAR1MAOASLC6A4
SCHEMBL28431900 0.72 TRPA1 (0.57) NPC1RAB9ATRPA1TAAR1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103965511-B A kind of dialkylphosphinate metal double salt fire retardant and preparation method thereof 江汉大学 2016-09-21 CN disclosed