Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 12/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28103810 | 1.00 | PIK3CD (0.43) | PIK3CDPIK3R1PIK3CGPIK3CBLMNA | |
| SCHEMBL17718344 | 0.87 | PIK3CD (0.47) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL28103798 | 0.87 | PIK3CD (0.47) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL28103801 | 0.87 | PIK3CG (0.44) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL28103803 | 0.87 | PIK3CG (0.44) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA | |
| SCHEMBL28103570 | 0.84 | PIK3CD (0.41) | PIK3CDPIK3R1PIK3CGPIK3CBLMNA | |
| SCHEMBL28103568 | 0.84 | PIK3CD (0.41) | PIK3CDPIK3R1PIK3CGPIK3CBLMNA | |
| SCHEMBL28103817 | 0.83 | LMNA (0.47) | LMNASMN1; SMN2 | |
| SCHEMBL28103819 | 0.83 | LMNA (0.47) | LMNASMN1; SMN2 | |
| SCHEMBL16583379 | 0.81 | PIK3CD (0.58) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104768952-B | PI3K inhibitors | 山东亨利医药科技有限责任公司 | 2016-10-19 | — | — | CN | disclosed |