Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DDO | Q99489 | 1/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | KLK1 | P06870 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16881188 | 0.89 | KMT2A (0.41) | KMT2AHCAR2KDM4EALDH1A1EPHX2 | |
| SCHEMBL28105743 | 0.87 | KMT2A (0.43) | KMT2AHCAR2KDM4EALDH1A1EPHX2 | |
| SCHEMBL28105209 | 0.81 | KMT2A (0.60) | KMT2AHCAR2KDM4EALDH1A1EPHX2 | |
| SCHEMBL16881357 | 0.78 | KMT2A (0.43) | KMT2AHCAR2KDM4EALDH1A1EPHX2 | |
| SCHEMBL16881413 | 0.77 | ATM (0.43) | ALDH1A1POLBBDKRB1KLKB1KLK1 | |
| SCHEMBL16891497 | 0.75 | BDKRB1 (0.36) | BDKRB1KLKB1KLK1 | |
| SCHEMBL16881310 | 0.73 | KMT2A (0.60) | KMT2AHCAR2KDM4EALDH1A1NR1H4 | |
| SCHEMBL29788856 | 0.72 | BDKRB1 (0.46) | KMT2ABDKRB1DPP4DPP8DPP7 | |
| SCHEMBL28379915 | 0.71 | DPP4 (0.35) | HCAR2ALDH1A1DPP4DPP8DPP7 | |
| SCHEMBL16881392 | 0.71 | BDKRB1 (0.39) | KMT2AALDH1A1MEN1BDKRB1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061480-B | Therapeutic inhibitory compounds | 莱福斯希医药公司 | 2020-02-28 | — | — | CN | disclosed |
| CN-106061480-A | Therapeutic inhibitory compounds | 莱福斯希医药公司 | 2016-10-26 | — | — | CN | disclosed |