Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | HTR2B | P41595 | 3/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16881310 | 0.89 | KMT2A (0.60) | KMT2AHDAC1HDAC6ALDH1A1MAPT | |
| SCHEMBL28105664 | 0.86 | RECQL (0.49) | KMT2AALDH1A1SMN1; SMN2KDM4ENR1H4 | |
| SCHEMBL28105743 | 0.82 | KMT2A (0.43) | KMT2AALDH1A1POLBKDM4ENR1H4 | |
| SCHEMBL16881056 | 0.81 | KDM4E (0.50) | KMT2AHDAC1HDAC6ALDH1A1MAPT | |
| SCHEMBL28105192 | 0.81 | KMT2A (0.40) | KMT2AALDH1A1POLBKDM4ENR1H4 | |
| SCHEMBL4403052 | 0.79 | MEN1 (0.52) | KMT2AHDAC1ALDH1A1RAB9APOLB | |
| SCHEMBL16880997 | 0.78 | KMT2A (0.47) | KMT2AALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL16891565 | 0.77 | KMT2A (0.48) | KMT2AHDAC1HDAC6ALDH1A1MAPT | |
| SCHEMBL5374862 | 0.77 | KMT2A (1.00) | KMT2AHDAC1HDAC6ALDH1A1MAPT | |
| SCHEMBL16880649 | 0.76 | KMT2A (0.47) | KMT2AHDAC1HDAC6ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061480-B | Therapeutic inhibitory compounds | 莱福斯希医药公司 | 2020-02-28 | — | — | CN | disclosed |
| CN-106061480-A | Therapeutic inhibitory compounds | 莱福斯希医药公司 | 2016-10-26 | — | — | CN | disclosed |