Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 8/20 | 0.34 |
| ▸ | KLK1 | P06870 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068166 | 0.81 | POLB (0.44) | POLBNPSR1L3MBTL1KLKB1KLK1 | |
| SCHEMBL29348988 | 0.81 | POLB (0.44) | POLBNPSR1L3MBTL1KLKB1KLK1 | |
| SCHEMBL21985427 | 0.81 | POLB (0.44) | POLBNPSR1L3MBTL1KLKB1SMN1; SMN2 | |
| SCHEMBL27033279 | 0.79 | KLKB1 (0.48) | POLBNPSR1KLKB1KLK1 | |
| SCHEMBL29859925 | 0.79 | KLKB1 (0.48) | POLBNPSR1KLKB1KLK1 | |
| SCHEMBL29859871 | 0.79 | POLB (0.45) | POLBNPSR1L3MBTL1KLKB1KLK1 | |
| SCHEMBL16880842 | 0.79 | POLB (0.45) | POLBNPSR1L3MBTL1KLKB1KLK1 | |
| SCHEMBL16880843 | 0.79 | POLB (0.42) | POLBNPSR1KLKB1KLK1 | |
| SCHEMBL28376490 | 0.78 | LMNA (0.47) | POLBNPSR1KLKB1KLK1LMNA | |
| SCHEMBL21169913 | 0.78 | PRMT5 (0.44) | POLBNPSR1L3MBTL1KLKB1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061480-A | Therapeutic inhibitory compounds | 莱福斯希医药公司 | 2016-10-26 | — | — | CN | disclosed |