Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.42 |
| ▸ | GAK | O14976 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11973471 | 0.84 | SLC40A1 (0.53) | SLC40A1LMNAALDH1A1CYP3A4 | |
| SCHEMBL28104838 | 0.83 | GAK (0.45) | MAPTMEN1KMT2ASLC40A1GAK | |
| SCHEMBL8655521 | 0.73 | MAPK1 (0.61) | MAPK1EPAS1MAPTMEN1KMT2A | |
| SCHEMBL9119799 | 0.73 | EPAS1 (0.57) | MAPK1EPAS1MAPTMEN1KMT2A | |
| SCHEMBL10570949 | 0.73 | EPAS1 (0.58) | MAPK1EPAS1MAPTMEN1KMT2A | |
| SCHEMBL11973755 | 0.72 | SLC40A1 (0.59) | SLC40A1LMNAALDH1A1 | |
| SCHEMBL2465309 | 0.72 | MAPT (0.63) | MAPK1EPAS1MAPTMEN1KMT2A | |
| SCHEMBL11973017 | 0.71 | MEN1 (0.48) | MEN1KMT2ASLC40A1LMNAALDH1A1 | |
| SCHEMBL11973534 | 0.70 | SLC40A1 (0.69) | MAPK1MAPTMEN1KMT2ASLC40A1 | |
| SCHEMBL7292666 | 0.70 | MAPT (0.65) | MAPK1EPAS1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103492028-B | Sulfonaminoquinoline hepcidin antagonists | 维福（国际）股份公司 | 2017-02-08 | — | — | CN | disclosed |