Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 6/20 | 0.69 |
| ▸ | NFKBIA | P25963 | 4/20 | 0.69 |
| ▸ | RELA | Q04206 | 4/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.48 |
| ▸ | MDM4 | O15151 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28105304 | 0.91 | SLC40A1 (0.66) | SLC40A1NFKBIARELAMAPK1AKR1B1 | |
| SCHEMBL11973679 | 0.81 | SLC40A1 (1.00) | SLC40A1NFKBIARELAMEN1KMT2A | |
| SCHEMBL5113791 | 0.81 | PDE10A (0.67) | SLC40A1NFKBIARELAMAPK1PDE10A | |
| SCHEMBL11972968 | 0.80 | SLC40A1 (0.86) | SLC40A1NFKBIARELAMEN1KMT2A | |
| SCHEMBL28105312 | 0.79 | SLC40A1 (0.64) | SLC40A1NFKBIARELAMEN1KMT2A | |
| SCHEMBL6836512 | 0.78 | MEN1 (0.68) | SLC40A1NFKBIARELAMAPK1AKR1B1 | |
| SCHEMBL7689987 | 0.77 | EGLN1 (0.64) | SLC40A1NFKBIARELAMAPK1MEN1 | |
| SCHEMBL28105485 | 0.77 | SLC40A1 (0.61) | SLC40A1NFKBIARELAMEN1KMT2A | |
| SCHEMBL8559386 | 0.76 | AKR1B1 (0.77) | MAPK1AKR1B1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL5445828 | 0.76 | HSP90AA1 (0.62) | SLC40A1NFKBIARELAMAPK1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103492028-B | Sulfonaminoquinoline hepcidin antagonists | 维福（国际）股份公司 | 2017-02-08 | — | — | CN | disclosed |