Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 19/20 | 0.46 |
| ▸ | MAP4K1 | Q92918 | 18/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16881106 | 0.85 | KLKB1 (0.51) | KLKB1MAP4K1 | |
| SCHEMBL17442588 | 0.83 | KLKB1 (0.64) | KLKB1MAP4K1 | |
| SCHEMBL17442676 | 0.70 | KLKB1 (0.58) | KLKB1MAP4K1 | |
| SCHEMBL28206157 | 0.66 | ROCK2 (0.44) | ROCK2 | |
| SCHEMBL16246731 | 0.66 | ROCK2 (0.44) | ROCK2 | |
| SCHEMBL28169395 | 0.66 | KLKB1 (0.46) | KLKB1MAP4K1ROCK2 | |
| SCHEMBL16891557 | 0.65 | KLKB1 (0.79) | KLKB1MAP4K1 | |
| SCHEMBL17920376 | 0.64 | KLKB1 (0.50) | KLKB1MAP4K1 | |
| SCHEMBL16891561 | 0.63 | KLKB1 (0.53) | KLKB1MAP4K1 | |
| SCHEMBL16881169 | 0.63 | KLKB1 (1.00) | KLKB1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061480-A | Therapeutic inhibitory compounds | 莱福斯希医药公司 | 2016-10-26 | — | — | CN | disclosed |