Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22149392 | 0.71 | UHRF1 (0.39) | LRRK2KMT2AKDM4E | |
| SCHEMBL18013016 | 0.71 | CCNA2 (0.36) | NPSR1MAPTCYP2C9ALOX15KMT2A | |
| SCHEMBL4588217 | 0.71 | — | — | |
| SCHEMBL30168270 | 0.70 | — | — | |
| SCHEMBL13034200 | 0.70 | — | — | |
| SCHEMBL2616794 | 0.68 | L3MBTL1 (0.47) | NPSR1KMT2AALDH1A1MAPK1 | |
| SCHEMBL1422106 | 0.68 | — | — | |
| SCHEMBL6026053 | 0.67 | NPSR1 (0.38) | NPSR1MAPTCYP2C9ALOX15KMT2A | |
| SCHEMBL790901 | 0.67 | KDM4E (0.44) | NPSR1MAPTCYP2C9ALOX15KMT2A | |
| SCHEMBL1509571 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104428293-B | Adjust the benzimidazole of TNF α | UCB生物制药私人有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-104470924-B | Imidazopyrazines derivant as TNF active regulator | UCB生物制药私人有限公司 | 2016-11-09 | — | — | CN | disclosed |