Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.87 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18044961 | 0.93 | BTK (1.00) | BTKKCNH2 | |
| SCHEMBL16676819 | 0.93 | BTK (1.00) | BTKKCNH2 | |
| SCHEMBL28281468 | 0.84 | BTK (0.71) | BTKKCNH2 | |
| SCHEMBL16671028 | 0.82 | BTK (1.00) | BTKKCNH2 | |
| SCHEMBL18044931 | 0.82 | BTK (1.00) | BTKKCNH2 | |
| SCHEMBL16676809 | 0.82 | BTK (1.00) | BTKKCNH2 | |
| SCHEMBL20998484 | 0.80 | BTK (0.79) | BTKKCNH2EGFRLCK | |
| SCHEMBL28106073 | 0.79 | BTK (0.78) | BTKKCNH2EGFRLCK | |
| SCHEMBL28106087 | 0.79 | BTK (0.78) | BTKKCNH2EGFRLCK | |
| SCHEMBL18044912 | 0.79 | BTK (0.73) | BTKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105939998-A | Heteroaryl compounds as btk inhibitors and uses thereof | 默克专利有限公司 | 2016-09-14 | — | — | CN | disclosed |