SCHEMBL28107168

SCHEMBL28107168

CNC(=O)CCCCCCCCC(N)=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
HDAC3 O15379 2/20 0.46
HDAC1 Q13547 2/20 0.46
HDAC2 Q92769 2/20 0.46
HDAC8 Q9BY41 2/20 0.46
HDAC6 Q9UBN7 2/20 0.46
HDAC5 Q9UQL6 2/20 0.46
FAAH O00519 4/20 0.43
SOAT1 P35610 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TP53 P04637 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C19 P33261 1/20 0.43
HSP90AA1 P07900 1/20 0.43
KDM4E B2RXH2 2/20 0.39
NAMPT P43490 1/20 0.39
MAPK1 P28482 1/20 0.39
DNM1 Q05193 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30416681 1.00 LMNA (0.46) LMNAHDAC3HDAC1HDAC2HDAC8
SCHEMBL30415482 1.00 LMNA (0.46) LMNAHDAC3HDAC1HDAC2HDAC8
SCHEMBL6682401 1.00 LMNA (0.46) LMNAHDAC3HDAC1HDAC2HDAC8
SCHEMBL30068381 1.00 LMNA (0.46) LMNAHDAC3HDAC1HDAC2HDAC8
SCHEMBL30416186 1.00 LMNA (0.46) LMNAHDAC3HDAC1HDAC2HDAC8
SCHEMBL6683840 0.97 LMNA (0.48) LMNAHDAC3HDAC1HDAC2HDAC8
SCHEMBL487785 0.92 LMNA (0.48) LMNAHDAC3HDAC1HDAC2HDAC8
SCHEMBL15436044 0.91 HSP90AA1 (0.57) FAAHSOAT1MEN1KMT2ATP53
SCHEMBL12333287 0.89 HDAC3 (0.55) LMNAHDAC3HDAC1HDAC2HDAC8
SCHEMBL5909483 0.89 HDAC3 (0.55) LMNAHDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110198957-A The functionalization and its composition in situ of polysaccharide 纳幕尔杜邦公司 2019-09-03 CN claimed
CN-111205282-B ER protein modulators and uses thereof 上海科技大学 2023-12-01 CN disclosed
CN-109804014-A polyolefin structure 三菱瓦斯化学株式会社 2019-05-24 CN disclosed
CN-104981345-B Laminate film 东洋纺株式会社 2018-05-01 CN disclosed
CN-107637605-A Flame-retardant mixture, its preparation and application thereof 科莱恩塑料和涂料有限公司 2018-01-30 CN disclosed
CN-104968494-B Gas barrier film 东洋纺株式会社 2018-01-02 CN disclosed
CN-104364305-B Comprise the flame-retardant mixture of fire retardant and aluminium phosphite, Its Preparation Method And Use 科莱恩金融(BVI)有限公司 2016-10-26 CN disclosed