Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 5/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28107220 | 0.82 | TBXAS1 (0.49) | TBXAS1CYP11B2CYP11B1MAOAPTGES2 | |
| SCHEMBL1605397 | 0.81 | TBXAS1 (0.54) | TBXAS1CYP11B2CYP11B1MAOAPTGES2 | |
| SCHEMBL1605159 | 0.80 | TBXAS1 (0.48) | TBXAS1CYP11B2CYP11B1MAOAPTGES2 | |
| SCHEMBL1605764 | 0.79 | TBXAS1 (0.51) | TBXAS1CYP11B2CYP11B1MAOAPTGES2 | |
| SCHEMBL1606071 | 0.78 | TBXAS1 (0.64) | TBXAS1CYP11B2CYP11B1MAOAPTGES2 | |
| SCHEMBL1606069 | 0.78 | TBXAS1 (0.46) | TBXAS1CYP11B2CYP11B1MAOAPTGES2 | |
| SCHEMBL1605125 | 0.78 | TBXAS1 (0.47) | TBXAS1CYP11B2CYP11B1MAOAPTGES2 | |
| SCHEMBL1606344 | 0.78 | TBXAS1 (0.52) | TBXAS1CYP11B2CYP11B1MAOAPTGES2 | |
| SCHEMBL1606827 | 0.76 | TBXAS1 (0.55) | TBXAS1CYP11B2CYP11B1MAOAPTGES2 | |
| SCHEMBL1606572 | 0.76 | PTGES2 (0.52) | TBXAS1PTGES2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104193725-B | Organic compound | 诺华股份有限公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-102076665-A | Organic compounds | NOVARTIS AG | 2011-05-25 | — | — | CN | disclosed |