SCHEMBL28107291

SCHEMBL28107291

CCCCCCCCNC(=S)SCCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.50
NFE2L2 Q16236 1/20 0.50
EPHX1 P07099 8/20 0.47
CASP2 P42575 1/20 0.42
ZDHHC20 Q5W0Z9 1/20 0.40
ZDHHC2 Q9UIJ5 1/20 0.40
NAAA Q02083 1/20 0.40
GBA1 P04062 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28158701 1.00 KEAP1 (0.50) KEAP1NFE2L2EPHX1CASP2ZDHHC20
SCHEMBL28883654 1.00 KEAP1 (0.50) KEAP1NFE2L2EPHX1CASP2ZDHHC20
SCHEMBL28037036 1.00 KEAP1 (0.50) KEAP1NFE2L2EPHX1CASP2ZDHHC20
SCHEMBL20897828 1.00 KEAP1 (0.50) KEAP1NFE2L2EPHX1CASP2ZDHHC20
SCHEMBL20897312 1.00 KEAP1 (0.50) KEAP1NFE2L2EPHX1CASP2ZDHHC20
SCHEMBL28359053 1.00 KEAP1 (0.50) KEAP1NFE2L2EPHX1CASP2ZDHHC20
SCHEMBL31122197 1.00 KEAP1 (0.50) KEAP1NFE2L2EPHX1CASP2ZDHHC20
Hydrochloric Acid SCHEMBL8084045 0.98 KEAP1 (0.49) KEAP1NFE2L2EPHX1CASP2ZDHHC20
SCHEMBL20897754 0.98 KEAP1 (0.49) KEAP1NFE2L2EPHX1CASP2ZDHHC20
SCHEMBL29121138 0.98 KEAP1 (0.49) KEAP1NFE2L2EPHX1CASP2ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110325377-A Pneumatic tire 株式会社普利司通 2019-10-11 CN disclosed
CN-110168065-A Low viscosity lubricating oil composition for turbomachinery 埃克森美孚研究工程公司 2019-08-23 CN disclosed
CN-107406632-B Rubber composition and tire 株式会社普利司通 2019-03-01 CN disclosed
CN-108329978-A A kind of polyethers Screw air compressor oil composition and preparation method thereof 盘锦北方沥青股份有限公司 2018-07-27 CN disclosed
CN-108138374-A Rubber is strengthened with fiber, rubber-fibre complex and uses its pneumatic tire 株式会社普利司通 2018-06-08 CN disclosed
CN-108138376-A Rubber is strengthened with fiber, rubber-fibre complex and uses its pneumatic tire 株式会社普利司通 2018-06-08 CN disclosed
CN-108138375-A Rubber is strengthened with fiber, rubber-fibre complex and uses its pneumatic tire 株式会社普利司通 2018-06-08 CN disclosed
CN-107406632-A Rubber composition and tire 株式会社普利司通 2017-11-28 CN disclosed
CN-106085559-B Lubricant compositions for automatic transmission 雅富顿化学公司 2017-09-19 CN disclosed
CN-106085559-A Lubricant compositions for automatic transmission 雅富顿化学公司 2016-11-09 CN disclosed