Acrylonitrile

Acrylonitrile

SCHEMBL28107388

C=CC#N.C=Cc1ccccc1Cl

nearest known ligand 0.75

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.75
TRPA1 O75762 1/20 0.50
GSR P00390 1/20 0.42
TSHR P16473 2/20 0.38
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.36
LMNA P02545 1/20 0.36
GRIN2D O15399 2/20 0.35
GRIN3B O60391 2/20 0.35
GRIN1 Q05586 2/20 0.35
GRIN2A Q12879 2/20 0.35
GRIN2B Q13224 2/20 0.35
GRIN2C Q14957 2/20 0.35
GRIN3A Q8TCU5 2/20 0.35
CHAT P28329 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
DYRK2 Q92630 1/20 0.34
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL27582978 0.89 ALDH1A1 (0.95) ALDH1A1TRPA1GSRTSHRLMNA
SCHEMBL678283 0.87 ALDH1A1 (1.00) ALDH1A1TRPA1GSRTSHRLMNA
SCHEMBL15848 0.87
SCHEMBL29389188 0.87
SCHEMBL27420160 0.84 ALDH1A1 (0.95) ALDH1A1TRPA1GSRTSHRLMNA
Hydrogen Sulfide SCHEMBL29004370 0.84 ALDH1A1 (0.95) ALDH1A1TRPA1GSRTSHRLMNA
Acrylonitrile SCHEMBL220918 0.84 ALDH1A1 (0.48) ALDH1A1TRPA1TSHRKDM4EGAA
Fluoride SCHEMBL27511553 0.84 ALDH1A1 (0.95) ALDH1A1TRPA1GSRTSHRLMNA
Methane SCHEMBL27317116 0.84 ALDH1A1 (0.95) ALDH1A1TRPA1GSRTSHRKDM4E
SCHEMBL28227709 0.84 ALDH1A1 (0.95) ALDH1A1TRPA1GSRTSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110023361-A Carbamate-urea-acrylic acid casting plate material 美国斯帕泰克塑料加工有限责任公司 2019-07-16 CN disclosed
CN-107033285-A Multilayer dental machining resin material 株式会社松风 2017-08-11 CN disclosed
CN-106963656-A The dentistry machining block composite material of fibre with the different sandwich construction of the transparency 株式会社松风 2017-07-21 CN disclosed
CN-104321913-B Cathode size compositions, lithium ion secondary battery negative pole and lithium rechargeable battery 日本瑞翁株式会社 2016-10-26 CN disclosed