Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVRL1 | P37023 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 6/20 | 0.42 |
| ▸ | ABL1 | P00519 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15568521 | 0.85 | FLT4 (0.61) | FLT4KDR | |
| SCHEMBL28107724 | 0.79 | FLT4 (0.69) | FLT4KDR | |
| SCHEMBL15567622 | 0.79 | FLT4 (0.67) | FLT4KDR | |
| SCHEMBL15568298 | 0.77 | FLT4 (0.70) | FLT4KDR | |
| SCHEMBL3333738 | 0.76 | EGFR (0.56) | ACVRL1ABL1 | |
| SCHEMBL3332350 | 0.74 | GAA (0.56) | ACVRL1ABL1NPC1RAB9APKM | |
| SCHEMBL13129156 | 0.73 | CETP (0.65) | NPC1RAB9AALDH1A1LMNAGAA | |
| SCHEMBL15523976 | 0.72 | FLT4 (0.45) | FLT4KDR | |
| SCHEMBL28592805 | 0.71 | CYP2C19 (0.64) | ACVRL1NPC1RAB9AALDH1A1PKM | |
| SCHEMBL23301458 | 0.70 | ABL1 (0.45) | ACVRL1ABL1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104736533-B | Vegfr3 inhibitor | 癌症治疗合作研究中心有限公司 | 2016-12-07 | — | — | CN | disclosed |