Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT4 | P35916 | 18/20 | 0.70 |
| ▸ | KDR | P35968 | 12/20 | 0.70 |
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15568521 | 0.84 | FLT4 (0.61) | FLT4KDR | |
| SCHEMBL28107724 | 0.84 | FLT4 (0.69) | FLT4KDR | |
| SCHEMBL15506704 | 0.83 | FLT4 (1.00) | FLT4KDR | |
| SCHEMBL15506861 | 0.82 | FLT4 (1.00) | FLT4KDR | |
| SCHEMBL15506726 | 0.78 | FLT4 (1.00) | FLT4KDR | |
| SCHEMBL15567622 | 0.78 | FLT4 (0.67) | FLT4KDR | |
| SCHEMBL28107473 | 0.77 | ACVRL1 (0.44) | FLT4KDR | |
| SCHEMBL15524050 | 0.75 | FLT4 (0.66) | FLT4KDR | |
| SCHEMBL15506853 | 0.74 | FLT4 (1.00) | FLT4KDR | |
| SCHEMBL15506620 | 0.74 | FLT4 (0.84) | FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2885291-A1 | VEGFR3 INHIBITORS | Cancer Therapeutics Crc Pty Limited (AU) | 2015-06-24 | — | — | EP | disclosed |
| WO-2014026243-A1 | VEGFR3 INHIBITORS | CANCER THERAPEUTICS CRC PTY LIMITED (AU) | 2014-02-20 | — | — | WO | disclosed |