Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 2/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27628461 | 0.88 | HSD11B1 (0.47) | HSD11B1HPGDSMN1; SMN2TSHRPI4KA | |
| SCHEMBL20198637 | 0.74 | HSD11B1 (0.55) | HSD11B1HPGDSMN1; SMN2TSHRAVPR1A | |
| SCHEMBL11978680 | 0.73 | MEN1 (0.50) | HPGDSMN1; SMN2TSHRAVPR1API4KA | |
| SCHEMBL17916170 | 0.72 | CETP (0.40) | HSD11B1HPGDTSHRPI4KAPI4K2B | |
| SCHEMBL27752152 | 0.72 | HSD11B1 (0.73) | HSD11B1HPGDSMN1; SMN2TSHRAVPR1A | |
| SCHEMBL195220 | 0.72 | HSD11B1 (0.73) | HSD11B1HPGDSMN1; SMN2TSHRAVPR1A | |
| SCHEMBL23846180 | 0.71 | HSD11B1 (0.72) | HSD11B1HPGDSMN1; SMN2TSHRAVPR1A | |
| SCHEMBL28352608 | 0.71 | HPGD (0.43) | HPGDSMN1; SMN2TSHRCACNA2D1ALDH1A1 | |
| SCHEMBL28356162 | 0.70 | SMN1; SMN2 (0.51) | HPGDSMN1; SMN2TSHRCACNA2D1ALDH1A1 | |
| SCHEMBL6619455 | 0.70 | TSHR (0.51) | HSD11B1HPGDTSHRNR1H3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103596957-B | Imidazopyridazines as AKT kinase inhibitors | 拜耳知识产权有限责任公司 | 2016-12-07 | — | — | CN | disclosed |