SCHEMBL28107991

SCHEMBL28107991

C=CC(=O)OCCC[SiH](OCC)OC(=O)c1ccccc1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.40
TSHR P16473 8/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
HPGD P15428 1/20 0.40
CYP3A4 P08684 4/20 0.39
MAPK1 P28482 2/20 0.39
TP53 P04637 1/20 0.39
ALDH1A1 P00352 8/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 2/20 0.34
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
PPARA Q07869 1/20 0.32
GPR35 Q9HC97 1/20 0.32
SCN1A P35498 1/20 0.32
SCN2A Q99250 1/20 0.32
SCN3A Q9NY46 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28108282 0.95 TSHR (0.43) THRBTSHRTDP1L3MBTL1HPGD
Phthalic Acid SCHEMBL9652344 0.78 TSHR (0.67) THRBTSHRTDP1L3MBTL1HPGD
SCHEMBL29625496 0.78 TSHR (0.53) THRBTSHRTDP1L3MBTL1HPGD
SCHEMBL29401268 0.78 TSHR (0.55) THRBTSHRTDP1L3MBTL1HPGD
SCHEMBL1110903 0.78 TSHR (0.53) THRBTSHRTDP1L3MBTL1HPGD
SCHEMBL7115629 0.78 TSHR (0.55) THRBTSHRTDP1L3MBTL1HPGD
Phthalic Acid SCHEMBL31121837 0.78 TSHR (0.53) THRBTSHRTDP1L3MBTL1HPGD
SCHEMBL81412 0.78 TSHR (0.59) THRBTSHRHPGDCYP3A4MAPK1
SCHEMBL28253738 0.77 TSHR (0.51) THRBTSHRHPGDCYP3A4MAPK1
SCHEMBL27613244 0.77 TSHR (0.51) THRBTSHRTDP1L3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109715753-A ADHESIVE SHEET LAMINATE, SHAPED ADHESIVE SHEET LAMINATE, AND METHOD FOR PRODUCING SAME 三菱化学株式会社 2019-05-03 CN disclosed
CN-106133600-B Photosensitive polymer combination, solder mask composition and capped printed wiring board 互应化学工业株式会社 2018-11-13 CN disclosed
CN-107848947-A Fluorochemical, living polymerization initiator, fluoropolymer, the manufacture method of fluoropolymer and anti-corrosion agent composition DIC株式会社 2018-03-27 CN disclosed
CN-106133600-A Photosensitive polymer combination, solder mask composition and capped printed substrate 互应化学工业株式会社 2016-11-16 CN disclosed