SCHEMBL28108282

SCHEMBL28108282

C=CC(=O)OCCC[SiH](OCC)OC(=O)c1ccccc1C(=O)O[SiH](CCCOC(=O)C=C)OCC

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.43
TDP1 Q9NUW8 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
HPGD P15428 1/20 0.43
CYP3A4 P08684 4/20 0.43
MAPK1 P28482 2/20 0.43
TP53 P04637 1/20 0.43
ALDH1A1 P00352 7/20 0.42
LMNA P02545 1/20 0.42
THRB P10828 3/20 0.41
HSD17B10 Q99714 3/20 0.36
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35
THRA P10827 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28107991 0.95 THRB (0.40) TSHRTDP1L3MBTL1HPGDCYP3A4
SCHEMBL81412 0.81 TSHR (0.59) TSHRHPGDCYP3A4MAPK1TP53
SCHEMBL28253738 0.80 TSHR (0.51) TSHRHPGDCYP3A4MAPK1TP53
SCHEMBL28098264 0.79 TSHR (0.50) TSHRHPGDCYP3A4TP53ALDH1A1
SCHEMBL110716 0.77 TSHR (0.58) TSHRHPGDCYP3A4MAPK1TP53
SCHEMBL16286758 0.76 TSHR (0.61) TSHRHPGDCYP3A4MAPK1TP53
SCHEMBL16286693 0.76 TSHR (0.61) TSHRHPGDCYP3A4MAPK1TP53
SCHEMBL1110904 0.75 TSHR (0.59) TSHRTDP1L3MBTL1HPGDCYP3A4
SCHEMBL7115632 0.75 TSHR (0.62) TSHRTDP1L3MBTL1HPGDCYP3A4
SCHEMBL28272157 0.75 TSHR (0.45) TSHRHPGDCYP3A4TP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106133600-B Photosensitive polymer combination, solder mask composition and capped printed wiring board 互应化学工业株式会社 2018-11-13 CN disclosed
CN-107003610-A Solder resist composition and covered printed wiring board 互应化学工业株式会社 2017-08-01 CN disclosed
CN-106133600-A Photosensitive polymer combination, solder mask composition and capped printed substrate 互应化学工业株式会社 2016-11-16 CN disclosed