Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28542828 | 0.95 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10NPSR1TP53 | |
| Alcohol SCHEMBL28128224 | 0.95 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10NPSR1TP53 | |
| Methyl Alcohol SCHEMBL27441488 | 0.86 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10NPSR1TP53 | |
| SCHEMBL10357730 | 0.83 | TP53 (0.41) | ALDH1A1LMNAHSD17B10NPSR1TP53 | |
| SCHEMBL10587125 | 0.83 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10NPSR1TP53 | |
| SCHEMBL10380822 | 0.83 | ALDH1A1 (0.47) | ALDH1A1LMNAHSD17B10NPSR1TP53 | |
| SCHEMBL30069233 | 0.83 | ALDH1A1 (0.47) | ALDH1A1LMNAHSD17B10NPSR1TP53 | |
| SCHEMBL135430 | 0.83 | ALDH1A1 (0.47) | ALDH1A1LMNAHSD17B10NPSR1TP53 | |
| Ethylamine SCHEMBL2230804 | 0.81 | TP53 (0.39) | ALDH1A1LMNAHSD17B10NPSR1TP53 | |
| Potassium Ion SCHEMBL28138096 | 0.80 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10NPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106353218-A | Continuous determination method of potassium nitrate and sodium nitrate mixed salt bath | 江南工业集团有限公司 | 2017-01-25 | — | — | CN | claimed |
| CN-106370685-A | Method for determining content of potassium in industrial potassium chloride | 吴俊逸 | 2017-02-01 | — | — | CN | disclosed |
| CN-106353218-A | Continuous determination method of potassium nitrate and sodium nitrate mixed salt bath | 江南工业集团有限公司 | 2017-01-25 | — | — | CN | disclosed |
| CN-106248709-A | A kind of measure the method for potassium content in fireworks and firecrackers firework medicament | 吴俊逸 | 2016-12-21 | — | — | CN | disclosed |
| CN-106124547-A | A kind of measure the method for potassium content in industrial potassium nitrate | 吴俊逸 | 2016-11-16 | — | — | CN | disclosed |