Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30996052 | 0.77 | PDE10A (0.44) | PDE10AMPOCYP3A4PNP | |
| SCHEMBL28043557 | 0.76 | CHRNA7 (0.46) | MPOCHRNA7CYP1A2CYP2D6HRH4 | |
| SCHEMBL30996042 | 0.76 | PDE10A (0.43) | PDE10ALMNAKMT2A | |
| SCHEMBL30996039 | 0.76 | HSP90AB1 (0.47) | PDE10AMPOLMNACYP1A2CYP3A4 | |
| SCHEMBL30996051 | 0.76 | TLR7 (0.43) | PDE10AMPOKMT2A | |
| SCHEMBL30996049 | 0.75 | PDE10A (0.45) | PDE10AMPOPDE4B | |
| SCHEMBL29694385 | 0.73 | PDE10A (0.46) | PDE10ALMNACYP3A4CYP2D6PNP | |
| SCHEMBL30996048 | 0.72 | PDE10A (0.52) | PDE10AMPOLMNACYP2D6 | |
| SCHEMBL30996041 | 0.72 | TLR8 (0.46) | PDE10AKMT2A | |
| SCHEMBL27835947 | 0.72 | PDE10A (0.44) | PDE10ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102083438-B | The quinoline of conditioning agent and related analogs as silent message regulatory factor | 西特里斯药业公司 | 2016-11-09 | — | — | CN | disclosed |