Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199173 | 0.98 | — | — | |
| Di(Hydroxyethyl)Ether SCHEMBL28085088 | 0.84 | TSHR (0.32) | SMN1; SMN2LMNAMAPTHPGDALDH1A1 | |
| SCHEMBL27445735 | 0.83 | LMNA (0.36) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL27263283 | 0.79 | — | — | |
| SCHEMBL28148120 | 0.79 | LMNA (0.34) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL27678339 | 0.79 | — | — | |
| SCHEMBL27333836 | 0.79 | LMNA (0.34) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL27259920 | 0.78 | HPGD (0.37) | SMN1; SMN2LMNANPC1RAB9AMAPT | |
| SCHEMBL27482160 | 0.78 | LMNA (0.37) | SMN1; SMN2LMNANPC1RAB9AMAPT | |
| SCHEMBL27692796 | 0.78 | MAPT (0.35) | SMN1; SMN2LMNANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106147087-A | A kind of automobile dustproof applies mechanically gum filler | 安徽微威胶件集团有限公司 | 2016-11-23 | — | — | CN | disclosed |