SCHEMBL28109809

SCHEMBL28109809

CCCCCCCCCCOC(=O)CC[SiH](OC)OC

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.56
DGKA P23743 1/20 0.56
HTR2C P28335 1/20 0.54
PRSS1 P07477 1/20 0.49
PRSS2 P07478 1/20 0.49
PRSS3 P35030 1/20 0.49
RAD52 P43351 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
FAAH O00519 1/20 0.47
DNM1 Q05193 1/20 0.47
EPHX1 P07099 1/20 0.44
TSHR P16473 2/20 0.43
PAM P19021 2/20 0.43
PRKCA P17252 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28835877 0.98 NAAA (0.53) NAAADGKAHTR2CPRSS1PRSS2
SCHEMBL11686884 0.81 NAAA (0.75) NAAADGKAHTR2CPRSS1PRSS2
SCHEMBL18929524 0.81 NAAA (0.75) NAAADGKAHTR2CPRSS1PRSS2
SCHEMBL339256 0.81 NAAA (0.75) NAAADGKAHTR2CPRSS1PRSS2
SCHEMBL54522 0.81 NAAA (0.75) NAAADGKAHTR2CPRSS1PRSS2
SCHEMBL187664 0.81 NAAA (0.75) NAAADGKAHTR2CPRSS1PRSS2
SCHEMBL68472 0.81 NAAA (0.75) NAAADGKAHTR2CPRSS1PRSS2
SCHEMBL37191 0.81 NAAA (0.75) NAAADGKAHTR2CPRSS1PRSS2
SCHEMBL333336 0.81 NAAA (0.75) NAAADGKAHTR2CPRSS1PRSS2
SCHEMBL886889 0.81 NAAA (0.75) NAAADGKAHTR2CPRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103172655-B Organosiloxane and its manufacture method containing anhydride group 信越化学工业株式会社 2017-10-17 CN disclosed
CN-102942585-B Succinic anhydride group containing cyclic organosiloxane, preparation thereof, organosiloxane composition and thermosetting resin composition 信越化学工业株式会社 2017-05-24 CN disclosed
CN-103131011-B Organosiloxane containing anhydride group and manufacture method thereof 信越化学工业株式会社 2016-12-21 CN disclosed