Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 4/20 | 0.35 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | IDH2 | P48735 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MDM4 | O15151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28167366 | 0.94 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3IDO1L3MBTL1 | |
| SCHEMBL28110549 | 0.94 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3IDO1L3MBTL1 | |
| SCHEMBL23923595 | 0.86 | ADRB1 (0.50) | SLC6A2SLC6A4SLC6A3GAAL3MBTL1 | |
| SCHEMBL28110017 | 0.86 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3IDO1GAA | |
| SCHEMBL23923596 | 0.86 | ADRB1 (0.50) | SLC6A2SLC6A4SLC6A3GAAL3MBTL1 | |
| SCHEMBL30317791 | 0.86 | ADRB1 (0.50) | SLC6A2SLC6A4SLC6A3GAAL3MBTL1 | |
| SCHEMBL28110018 | 0.86 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3IDO1GAA | |
| SCHEMBL16191051 | 0.84 | RXFP1 (0.41) | SLC6A2SLC6A4SLC6A3IDO1GAA | |
| SCHEMBL28046490 | 0.83 | IDO1 (0.48) | SLC6A2SLC6A4SLC6A3IDO1GAA | |
| SCHEMBL10405701 | 0.83 | IDO1 (0.48) | SLC6A2SLC6A4SLC6A3IDO1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507899-B | Phenol derivative, preparation method and medical application thereof | 四川海思科制药有限公司 | 2016-11-30 | — | — | CN | disclosed |