Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29403877 | 0.93 | ACHE (1.00) | ACHEALDH1A1CYP3A4L3MBTL1MAPT | |
| SCHEMBL12518 | 0.93 | ACHE (1.00) | ACHEALDH1A1CYP3A4L3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL27523444 | 0.90 | ACHE (0.95) | ACHEALDH1A1CYP3A4L3MBTL1MAPT | |
| Ammonia Solution, Strong SCHEMBL27765317 | 0.90 | ACHE (0.95) | ACHEALDH1A1CYP3A4L3MBTL1MAPT | |
| Methylamine SCHEMBL15398524 | 0.88 | ACHE (0.90) | ACHEALDH1A1CYP3A4L3MBTL1MAPT | |
| Formaldehyde SCHEMBL27962744 | 0.84 | ACHE (0.60) | ACHEALDH1A1CYP3A4L3MBTL1MAPT | |
| SCHEMBL11719616 | 0.81 | ACHE (0.69) | ACHEALDH1A1CYP3A4L3MBTL1MAPT | |
| Formaldehyde SCHEMBL10355974 | 0.80 | MAOB (0.57) | ACHEALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL23709118 | 0.79 | ACHE (0.74) | ACHEALDH1A1CYP3A4L3MBTL1MAPT | |
| SCHEMBL11131043 | 0.79 | ACHE (0.74) | ACHEALDH1A1CYP3A4L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083653-A | The synthetic method of Ormetoprim intermediate cinnamonitrile | 江苏天和制药有限公司 | 2016-11-09 | — | — | CN | disclosed |