Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | CD44 | P16070 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5940564 | 0.89 | KDM4E (0.45) | KDM4EPOLBALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL4598275 | 0.87 | MEN1 (0.44) | KDM4EPOLBALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8234056 | 0.81 | CRBN (0.45) | KDM4EPOLBALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL2061352 | 0.80 | CD44 (0.43) | KDM4EPOLBALDH1A1SMN1; SMN2CD44 | |
| SCHEMBL4919855 | 0.79 | TYK2 (0.55) | POLBALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6744852 | 0.79 | MEN1 (0.39) | KDM4EPOLBALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL18131339 | 0.79 | CES2 (0.44) | POLBMEN1KMT2AMAPT | |
| SCHEMBL28110420 | 0.79 | CA12 (0.47) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL6648364 | 0.76 | KDM4E (0.51) | KDM4EPOLBALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL5564083 | 0.76 | CD44 (0.39) | KDM4EPOLBALDH1A1SMN1; SMN2CD44 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146414-A | Quinazoline diones analog derivative and its production and use | 浙江大学 | 2016-11-23 | — | — | CN | disclosed |